Odontogenic tumors are heterogeneous group of lesions with diverse histopathological and clinical features. Ameloblastic fibro-dentinoma. The ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumor. .. It is also distinguishable from ameloblastic fibro-dentinoma not only because it. Peripheral ameloblastic fibro-dentinoma (AFD) is an extremely rare benign mixed odontogenic tumor. From a review of the English-language literature, to the.

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Odontogenic Tumors and Allied Lesions. Considerably more information on the AFD has to be collected in order dntinoma better understand the lesion, its biological behavior, risk of malignant transformation and relationship to the other AF-related lesion. View at Google Scholar J. Here, we report a case of aggressive AFD that presented as a rapidly growing mass associated with pain and presenting with resorption and perforation of the lingual cortical plate.

While in some other cases, hyalinised area containing entrapped cells has been considered as an abortive dentine or dentinoid tissue because of its proximity to the odontogenic epithelial. Please review our privacy policy. The substance of the radiolucent area showed few flecks of radioopacity.

The first is a neoplastic lesion, ameloblzstic if left in ameloblastiic does not appear to mature further.

Two additional pathologies, peripheral ameloblastoma and calcifying epithelial odontogenic tumor, should also be distinguished [ 4 ]. According to the recent World Health Organization classification of Odontogenic Tumours published in1 AFO belongs to the group of lesions with odontogenic epithelium with odontogenic ectomesenchyme, with or without hard tissue formation.

A majority of AFO ameeloblastic intraosseous and is associated with unerupted teeth. On the other hand, the compound odontoma is considered as a separate entity resulting from a locally hyperactivity of the dental lamina.

Ameloblastic fibro-odontoma

Localized reactive hyperplastic lesions in gingiva can be classified into 4 subcategories: Presence of tooth germ elements, e. Common signs and symptoms of AFO are asymptomatic swelling, delayed tooth eruption in the affected region and a well-defined mixed radiological appearance that is similar to other odontogenic neoplastic formations, such as immature complex odontoma, calcifying epithelial odontogenic tumour and adenomatoid odontogenic tumour.


Sitemap What’s New Feedback Disclaimer. The histopathologic examination of the soft tissue revealed numerous cords and follicles of odontogenic epithelium exhibiting peripheral ameloblast-like cells within primitive ectomesenchymal tissue Fig. Owing to the formation of dentine, whether a primitive osteodentin or the very rare mature tubular type of dentine, the tumor appears as a mixed radioopaque and radiolucent lesion with well-defined borders.

Many small blood vessels appeared in the connective tissue surrounding the odontogenic epithelium. It is divided into two types on the stage of the development, immature and mature type.

Aggressive atypical ameloblastic fibrodentinoma: Report of a case

The probing depths of denitnoma tooth were within normal range. Here we present a case of an aggressive ameloblastic fibrodentinoma which was radically excised in the light of clinical and histological presentation followed by reconstruction of mandible. Despite numerous efforts however, there is still considerable confusion concerning the nature and interrelationship of these mixed odontogenic tumors and related lesions.

The swelling extended from the corner of the mouth to the angle of the mandible [ Figure 1 ]. The tumor had caused expansion of the buccal dentinomz lingual cortical plate with perforation at some places. Hematoxylin and eosin staining for the gingival lesion.

Ameloblastic fibrodentinoma AFD is a rare tumor and is considered as denitnoma histological variant of AF showing inductive changes that lead to the formation of dentin. A diffuse swelling over the right anterior maxilla with obliteration of the nasolabial fold Click here to view.

Case Reports in Dentistry

Because peripheral AFO is so rare, there is no published study that estimates its recurrence rate after surgical excision. Histological assessment revealed a final diagnosis of ameloblastic fibro-odontoma. In support of this latter proposition, Slootweg[ denrinoma ] analyzed 33 mixed odontogenic tumors and found that the mean age of the patients with ameloblastic fibroodontoma was lower than that of the patients with AF.

Ameloblastuc orthopantomogram revealed a well-defined radiolucency measuring about 4. The tendency of the tumor to recur and to undergo malignant transformation also denotes its neoplastic character. After we had consulted with periodontics and oral-maxillofacial surgery specialists, we suggested an excisional biopsy under general anesthesia for the patient.


There was no recurrence after the 1-year follow-up. A study of 1, cases from Northern California and comparison to studies from other parts of cibro world.

None, Conflict of Interest: Footnotes Source of Support: Swelling involving the buccal vestibule extending from the region of the right maxillary central incisor to the fi rst premolar Click here to view.

Indian J Dent Res ; Relative frequency of central odontogenic tumors: Embryonic and other stem cells have long telomeres, firo become shorter during differentiation or aging but are stabilized again in tumorigenesis [ 25 ]. Khalam were the surgeons, Dr.

Ameloblastic fibroma and related lesions constitute a group of lesions, which range in biologic behaviour from true neoplasms to hamartomas. Because of the presence of dentin only, and complete absence of enamel even in multiple sections, the present case was considered as ameloblastic fibrodentinoma.

The WHO distinguishes odontogenic sarcoma devoid of dental hard tissue AFS from those displaying focal evidence of dentinoid AFDS or dentinoid plus enameloid AFOSbut the WHO panel acknowledges that presence or absence of dental hard tissue in an odontogenic sarcoma is of no prognostic significance. The buccal and lingual vestibule was obliterated and the expansion of lingual cortical plate was relatively higher.

Conservative excision of the tumor is the treatment of choice. The recurrence rate of intraosseous AFO is uncommon: Therefore, a radical resection followed by resection was the treatment of choice.

National Center for Biotechnology InformationU. The malignant counterparts of AF, AFD and AFO are ameloblastic fibrosarcoma, ameloblastic fibrodentinosarcoma and ameloblastic fibroodontosarcoma, respectively. View at Google Scholar A. Although the mechanism of malignant transformation of AF and other related benign mixed odontogenic tumors remain unsettled, multiple surgical procedures of recurrent lesions remain one of the important factors in their malignant transformation.

The slides were counterstained with Mayer hematoxylin and photographed using an optical microscope BX61; Olympus, Tokyo, Japan equipped with an imaging system Stream; Olympus.

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